ea0013s24 | Endocrine stem cells | SFEBES2007
Nir Tomer
, Dor Yuval
Understanding the mechanisms regulating pancreatic beta cell mass is a major challenge in pancreas biology with direct clinical implications for future therapies to diabetes. Key questions in this field regard the regenerative potential of beta cells, the identity of the cell of origin for regenerating beta cells and the nature of signals that govern beta cell homeostasis. We have developed a transgenic mouse system for conditional ablation of beta cells, ...